Systems approaches for the discovery of combinatorial therapies for complex disorders

Call: Systems approaches for the discovery of combinatorial therapies for complex disorders

Programme

Health, Demographic Change and Wellbeing

Description of programme
"Health, Demographic Change and Wellbeing"

Responding to the challenge of an aging population, research and innovation (R&I) under Horizon 2020 is an investment in better health for all. It aims to keep older people active and independent for longer and supports the development of new, safer and more effective interventions. R&I under Horizon 2020 also contributes to the sustainability of health and care systems.

Link

Link to Programme

Call

Systems approaches for the discovery of combinatorial therapies for complex disorders

Description of call
"Systems approaches for the discovery of combinatorial therapies for complex disorders"

Many complex disorders pose a challenge to identify the most effective therapeutic interventions because current therapies often target specific aspects of a disease, without achieving complete control or the best possible results for patients. Due to the multiple causes of such diseases and the heterogeneity between patients, approaches directed at single targets have had limited efficacy, overlooking important factors involved in disease pathophysiology. Hence, a promising therapeutic approach to meet this challenge is to combine different therapies, while increasing therapeutic efficacy in a cost-effective manner. Research should aim to understand at systems level the pathophysiology of a disorder in groups of patients responding well or poorly to particular therapies and further develop combinatorial therapies tailored to the needs of individuals or stratified patient groups.

Link

Link to Call

Thematic Focus

Innovation, Research, Health

Funding area

EU Member States
Albania / Shqipëria
Bosnia and Herzegovina
Iceland / Ísland
Moldova
Montenegro / Crna Gora/Црна Гора
North Macedonia / Северна Македонија
Norway / Norge
Serbia / Сpбија
Switzerland / Schweiz / Suisse / Svizzera
Turkey / Türkiye
Ukraine / Україна Oukraïna
Others

Origin of Applicant

Eligible applicants

Education and Training Centres, Federal State / Region / City / Municipality / Local Authority, Research Institution, Lobby Group / Professional Association / Trade Union, International Organization, Small and Medium Sized Enterprises, SMEs (between 10 and 249 employees), Microenterprises (fewer than 10 employees), NGO / NPO, University, Enterprise (more than 250 employees or not defined), Association

Applicant details

All legal entities located in the EU or in Third Countries can participate in Horizon 2020.

Project Partner

Yes

Project Partner Details

As a principle all projects (except coordination and support activities) must comprise at least 3 partners from at least 3 EU Member States or other eligible countries.

Further info

This call follows a two-stage submission procedure. For the first stage, a short proposal of max. 10 pages needs to be submitted. Maximum 3 months after the submission, the applicants selected will be notified and invited to submit their full proposal until 16.04.2019.

Type of Funding

Grant

Financial details

Total call-budget: 50 million €
Indicative budget per project: 3-4 million €
Co-financing rate: max. 100%

Submission

Online via Participant Portal

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