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  1. An institution, body, office or agency established by or based on the Treaty on European Union and the Treaties establishing the European Communities.

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    An intergovernmental organization having legal personality under public international law or a specialized agency established by such an international organization. An international organization, the majority of whose members are Member States or Associated Countries and whose main objective is to promote scientific and technological cooperation in Europe, is an International Organization of European Interest.

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    A microenterprise, a small or medium-sized enterprise (business) as defined in EU Recommendation 2003/361. To qualify as an SME for EU funding, an enterprise must meet certain conditions, including (a) fewer than 250 employees and (b) an annual turnover not exceeding EUR 50 million and/or an annual balance sheet total not exceeding EUR 43 million. These ceilings apply only to the figures for individual companies.

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Call key data

Use cases for the UNCAN.eu research data platform

Funding Program

EU Missions in Horizon Europe

Call number

HORIZON-MISS-2024-CANCER-01-01

deadlines

Opening
18.04.2024

Deadline
18.09.2024 17:00

Funding rate

100 %

Call budget

€ 30,000,000.00

Estimated EU contribution per project

€ 30,000,000.00

Link to the call

ec.europa.eu

Link to the submission

ec.europa.eu

Call content

short description

The aim of this topic is to operationalise the UNCAN.eu research data platform foreseen in the Cancer Mission implementation plan, through a series of use-cases. To this goal, proposals are expected to develop tools supporting researchers to access, manage and analyse cancer digital data, building among others on resources developed by EOSC4cancer.

Call objectives

The successful proposal should:

  • Develop the UNCAN.eu platform by integrating and, where relevant, complementing existing or planned data nodes of European research infrastructures and/or other national infrastructures that may link various cancer data holders across Member States and Associated Countries (e.g. hospitals, research centres, comprehensive cancer centres, etc.). The number of Member States involved should be sufficient to demonstrate scalability and flexibility of the UNCAN.eu platform while allowing for stepwise onboarding of more countries.
  • Provide tools, services and workflows to researchers across data nodes for dataset creation, standardisation, data discovery, secure access, management, visualization, harmonization, analysis and other functions as appropriate. This task should capitalise on EOSC4cancer's achievements, integrating and expanding as appropriate the available tools and solutions. It should also take advantage of the European Health Data Space and the European Open Science Cloud frameworks.
  • Design and implement a rich and diverse portfolio of use-cases to inform, steer the development and demonstrate the validity of the UNCAN.eu platform. Use cases should focus on research questions that are in line with the Cancer Mission objectives and that may advance the understanding of mechanisms involved in cancer development and progression beyond the current state of the art. At least one use-case should target a cancer type with a 5-year overall survival of less than 50% from the time of diagnosis. A second use-case should target paediatric cancer.
  • At the same time, use-cases should be functional to the design and implementation of UNCAN.eu to increase the diversity of digital tools and services available for cancer researchers. The mobilisation and integration of a large amount of research and real word data beyond current practice and a balanced participation of clinicians, disease experts and data scientists will be essential to achieve the objectives of this topic. Due attention should be paid to sex and gender, disaggregating the data as appropriate.
  • The successful consortium should develop innovative approaches, to integrate and analyse heterogeneous data from multiple sources and different research domains, including the participation of the necessary interdisciplinary set of European infrastructures and national data nodes. In this regard, at least one use-case should integrate imaging, digital pathology and genomic data, using and/or contributing with new data sources to the Genomics Data Infrastructure (GDI) and Cancer Image Europe (EUCAIM).
  • Give emphasis to data being managed and shared in line with the FAIR principles, and the concept of FAIR-by-design is applied wherever possible. The applicants must demonstrate that the necessary data sources are, or will be, effectively and timely available. During the project lifetime, new data sources that might become available at a later stage can be accommodated as well as allowing additional data holders to join the UNCAN.eu platform. Results must be open source and made available through a public repository under a permissive license. Open access data should be provided whenever possible.
  • Give due consideration to, and establish appropriate links with, EU-funded initiatives such as EHDS-related governance and implementation actions, the European Network of Cancer Registries.
  • Foresee to establish links with the successful proposal resulting from the topic HORIZON-MISS-2024-CANCER-01-02 ‘Support dialogue towards the development of national cancer data nodes'.

This topic requires the effective contribution of SSH disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, to produce meaningful and significant effects enhancing the societal impact of the related research activities.

The Commission will facilitate coordination. Therefore, proposals should include a budget for networking, attendance at meetings, and potential joint activities without the prerequisite to give details of these at this stage. Examples are organising joint workshops, establishing best practices, joint communication or citizen engagement activities with projects funded under other clusters and pillars of Horizon Europe, or other EU programmes, as appropriate.

Successful proposal will be asked to join the 'Understanding' cluster for the Mission on Cancer established in 2022. The details of joint activities will be defined during the grant agreement preparation phase and during the life of the project.

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Expected results

 Proposal(s) under this topic are expected to contribute to all of the following outcomes:

  • The UNCAN.eu platform is developed by federating a network of cancer data nodes built on European and national computing infrastructures that link different cancer data holders across European countries.
  • Use-cases focusing on the understanding of cancer initiation and progression are designed and implemented by multidisciplinary teams to develop tools and services for working with FAIR data.
  • Researchers and clinicians use the electronic resources provided by the UNCAN.eu platform to access, manage and analyse data of heterogeneous types and belonging to different research domains at an unprecedented scale.

Eligibility Criteria

Regions / countries for funding

EU Member States, Overseas Countries and Territories (OCT)
Moldova (Moldova), Albania (Shqipëria), Armenia (Հայաստան), Azerbaijan (Azərbaycan), Belarus (Беларусь), Bosnia and Herzegovina (Bosna i Hercegovina / Босна и Херцеговина), Faeroes (Føroyar / Færøerne), Georgia (საქართველო), Iceland (Ísland), Israel (ישראל / إِسْرَائِيل), Kosovo (Kosova/Kosovë / Косово), Montenegro (Црна Гора), Morocco (المغرب), New Zealand (Aotearoa), North Macedonia (Северна Македонија), Norway (Norge), Serbia (Srbija/Сpбија), Tunisia (تونس /Tūnis), Türkiye, Ukraine (Україна), United Kingdom

eligible entities

Education and training institution, International organization, Non-Profit Organisation (NPO) / Non-Governmental Organisation (NGO), Other, Private institution, incl. private company (private for profit), Public Body (national, regional and local; incl. EGTCs), Research Institution incl. University, Small and medium-sized enterprise (SME)

Mandatory partnership

Yes

Project Partnership

To be eligible for funding, applicants must be established in one of the following countries:

  • the Member States of the European Union, including their outermost regions
  • the Overseas Countries and Territories (OCTs) linked to the Member States
  • third countries associated to Horizon Europe - see list of particpating countries

Only legal entities forming a consortium are eligible to participate in actions provided that the consortium includes, as beneficiaries, three legal entities independent from each other and each established in a different country as follows:

  • at least one independent legal entity established in a Member State; and
  • at least two other independent legal entities, each established in different Member States or Associated Countries.

Any legal entity, regardless of its place of establishment, including legal entities from non-associated third countries or international organisations (including international European research organisations) is eligible to participate (whether it is eligible for funding or not), provided that the conditions laid down in the Horizon Europe Regulation have been met, along with any other conditions laid down in the specific call topic.

A ‘legal entity’ means any natural or legal person created and recognised as such under national law, EU law or international law, which has legal personality and which may, acting in its own name, exercise rights and be subject to obligations, or an entity without legal personality.

Specific cases:

  • Affiliated entities — Affiliated entities (i.e. entities with a legal or capital link to a beneficiary which participate in the action with similar rights and obligations to the beneficiaries, but which do not sign the grant agreement and therefore do not become beneficiaries themselves) are allowed, if they are eligible for participation and funding.
  • Associated partners — Associated partners (i.e. entities which participate in the action without signing the grant agreement, and without the right to charge costs or claim contributions) are allowed, subject to any conditions regarding associated partners set out in the specific call conditions.
  • Entities without legal personality — Entities which do not have legal personality under their national law may exceptionally participate, provided that their representatives have the capacity to undertake legal obligations on their behalf, and offer guarantees to protect the EU’s financial interests equivalent to those offered by legal persons.
  • EU bodies — Legal entities created under EU law including decentralised agencies may be part of the consortium, unless provided for otherwise in their basic act.
  • Joint Research Centre (‘JRC’)— Where provided for in the specific call conditions, applicants may include in their proposals the possible contribution of the JRC but the JRC will not participate in the preparation and submission of the proposal. Applicants will indicate the contribution that the JRC could bring to the project based on the scope of the topic text. After the evaluation process, the JRC and the consortium selected for funding may come to an agreement on the specific terms of the participation of the JRC. If an agreement is found, the JRC may accede to the grant agreement as beneficiary requesting zero funding or participate as an associated partner, and would accede to the consortium as a member.
  • Associations and interest groupings — Entities composed of members (e.g. European research infrastructure consortia (ERICs)) may participate as ‘sole beneficiaries’ or ‘beneficiaries without legal personality’. However, if the action is in practice implemented by the individual members, those members should also participate (either as beneficiaries or as affiliated entities, otherwise their costs will NOT be eligible.

other eligibility criteria

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 3 (Implementation). The cumulative threshold will be 12.

Additional information

Topics

Digitalisation, Digital Society, ICT, 
Health, Social Services, Sports

Relevance for EU Macro-Region

EUSAIR - EU Strategy for the Adriatic and Ionian Region, EUSALP - EU Strategy for the Alpine Space, EUSBSR - EU Strategy for the Baltic Sea Region, EUSDR - EU Strategy for the Danube Region

UN Sustainable Development Goals (UN-SDGs)

Additional Information

All proposals must be submitted electronically via the Funders & Tenders Portal electronic submission system (accessible via the topic page in the Search Funding & Tenders section). Paper submissions are NOT possible.

Proposals must be complete and contain all parts and mandatory annexes and supporting documents, e.g. plan for the exploitation and dissemination of the results including communication activities, etc.

The application form will have two parts:

  • Part A (to be filled in directly online) contains administrative information about the applicant organisations (future coordinator and beneficiaries and affiliated entities), the summarised budget for the proposal and call-specific questions;
  • Part B (to be downloaded from the Portal submission system, completed and then assembled and re-uploaded as a PDF in the system) contains the technical description of the project.

Annexes and supporting documents will be directly available in the submission system and must be uploaded as PDF files (or other formats allowed by the system).

The limit for a full application (Part B) is 70 pages.

Call documents

Horizon Missions 2023-2024Horizon Missions 2023-2024(2860kB)

Contact

National Contact Points for Horizon Europe
Website

EU Missions in Horizon Europe
RTD-HORIZON-EUROPE-MISSIONS@ec.europa.eu
Website

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