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Call key data
Global coordination of exposome research
|Funding Program||Horizon Europe - Cluster 1 - Destination 2: Living and working in a health-promoting environment|
|Call budget||€ 3,000,000.00|
|Estimated EU contribution per project||€ 3,000,000.00|
|Link to the call||ec.europa.eu|
|Link to the submission||ec.europa.eu|
The concept of the exposome refers to the totality of environmental exposures from conception onwards, including its external (e.g. diet, lifestyle, occupational and environmental factors) and internal components (e.g. epigenomics, metabolomics). Developing a comprehensive Human Exposome Project would present a fundamental shift in looking at health, by moving research away from ‘one exposure, one disease’ understanding to a more complex picture upon which to build solid, cost-effective preventive actions and policies. At its most complete, the efforts could resemble in scope the Human Genome Project.
The European Human Exposome Network (EHEN), a cluster of 9 projects funded since 2020 for five years from Horizon 2020, is currently the world’s largest network of projects studying the impact of environmental exposure on human health with an exposome angle. Together, the network of projects aims to study the combination of exposures to pollutants and other stressors, across different life stages and socio-economic conditions, via a number of exposure vehicles such as consumption patterns, lifestyle and working and living environment, and their collective effect on human health.
At the international level, some related activities are ongoing in, e.g., the US (National Institute for Environmental Health Sciences) and Japan. Currently, there is only sporadic cooperation initiatives between the ongoing research at the EU level and important research groups outside Europe. However, in order to fulfil the promise of deciphering the human exposome, a large-scale effort similar to the Human Genome Project could be envisaged, for which a preparatory coordination and support action would be highly useful to identify and discuss the research needs and specific areas of potential cooperation at the global level. Additionally, both at the European and global level better coordination is essential to foster new opportunities to collect, harmonise, combine and analyse large data sets emanating from new and evolving technologies. This offers also new possibilities to understand the pathways leading from a multitude of environmental exposures to the global health burden of common chronic diseases. Standardisation and interoperability of data is also needed to assure access to quality data sources at the European and global level.
On the policy side, the outcomes of advancing the exposome research can touch upon and contribute to a better implementation of a wide range of policies and EU priorities such as the EU Chemicals Strategy, Zero Pollution Action Plan, the European Green Deal and climate policies, among others. The benefits of cooperation would also extend to international initiatives such as activities of the World Health Organization related to environment and health and the United Nations activities on climate and environment.
Accordingly, proposals should cover, among others, most of the following activities:
Proposals should interact with existing research infrastructures, services and research projects in the area of the exposome (namely the European Human Exposome Network but also other related projects and actions supported through Horizon 2020 and Horizon Europe) and build on and integrate the work being developed in these initiatives. The composition of the applicant consortia should ensure a broad and balanced geographical representation of Member States and Associated Countries and the proposals should involve also Widening Member States and Associated Countries. International cooperation beyond EU with interested parties is required.
|Expected effects and impacts|
|Regions / countries for funding||EU Member States, Overseas Countries and Territories (OCT)|
Moldova (Moldova), Albania (Shqipëria), Armenia (Հայաստան), Bosnia and Herzegovina (Bosna i Hercegovina / Босна и Херцеговина), Faeroes (Føroyar / Færøerne), Georgia (საქართველო), Island (Ísland), Israel (ישראל / إِسْرَائِيل), Kosovo (Kosova/Kosovë / Косово), Montenegro (Црна Гора), Morocco (المغرب), North Macedonia (Северна Македонија), Norway (Norge), Serbia (Srbija/Сpбија), Tunisia (تونس /Tūnis), Türkiye, Ukraine (Україна), United Kingdom
|eligible entities||EU Body, Education and training institution, International organization, Natural Person, Non-Profit Organisation (NPO) / Non-Governmental Organisation (NGO), Other, Private institution, incl. private company (private for profit), Public Body (national, regional and local; incl. EGTCs), Research Institution incl. University, Small and medium-sized enterprise (SME)|
To be eligible for funding, applicants must be established in one of the following countries:
Applications may be submitted by one or more legal entities, which may be established in a Member State, Associated Country or, in exceptional cases and if provided for in the specific call conditions, in another third country.
In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, legal entities established in the United States of America may exceptionally participate as a beneficiary or affiliated entity, and are eligible to receive Union funding.
Coordinators of projects must be legal entities established in an EU Member State or Associated Country.
In order to achieve the expected objectives, namely the establishment of a forward-looking cooperation framework in the area of the exposome, the consortium must include at least one legal entity established in a country other than a Member State or an Associated Country.
Any legal entity, regardless of its place of establishment, including legal entities from non-associated third countries or international organisations (including international European research organisations) is eligible to participate (whether it is eligible for funding or not), provided that the conditions laid down in the Horizon Europe Regulation have been met, along with any other conditions laid down in the specific call topic.
A ‘legal entity’ means any natural or legal person created and recognised as such under national law, EU law or international law, which has legal personality and which may, acting in its own name, exercise rights and be subject to obligations, or an entity without legal personality.
|other eligibility criteria|
If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).
Administration & Governance, Institutional Capacity & Cooperation,
Health, Social Services, Sports
|Relevance for EU Macro-Region||EUSAIR - EU Strategy for the Adriatic and Ionian Region, EUSALP - EU Strategy for the Alpine Space, EUSBSR - EU Strategy for the Baltic Sea Region, EUSDR - EU Strategy for the Danube Region|
|UN Sustainable Development Goals (UN-SDGs)|
All proposals must be submitted electronically via the Funders & Tenders Portal electronic submission system (accessible via the topic page in the Search Funding & Tenders section). Paper submissions are NOT possible.
Proposals must be complete and contain all parts and mandatory annexes and supporting documents, e.g. plan for the exploitation and dissemination of the results including communication activities, etc.
The application form will have two parts:
Annexes and supporting documents will be directly available in the submission system and must be uploaded as PDF files (or other formats allowed by the system).
The limit for a full application (Part B) is 30 pages.
The award criteria are described in General Annex D. The following exceptions apply: The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 3 (Implementation). The cumulative threshold will be 12.
|Call documents|| HE-Work Programme 2023-2024, Cluster 1, Destination 2 (383kB)
|Contact||National Contact Points for Horizon Europe |
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