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Call key data
CAPACITY BUILDING CAP2B
Funding Program
Interregional Innovation Investments
Call number
I3-2026-CAP2B
deadlines
Opening
23.10.2025
Deadline
19.03.2026 17:00
Funding rate
100%
Call budget
€ 9,800,000.00
Estimated EU contribution per project
between € 500,000.00 and € 1,500,000.00
Link to the call
Link to the submission
Call content
short description
The overall objective of the I3 Strand 2b is to build capacity in less developed regions to develop and strengthen their regional innovation ecosystems and value chains through coordinated and interlinked investments in several regions. This call for proposals aims to improve the capacity of public authorities and innovation intermediaries (e.g. clusters) to support companies in the identification of investment portfolios at an interregional scale.
Call objectives
The purpose of this activity is to build capacities for a successful participation in Strand 1 or Strand 2a calls, enhancing interregional cooperation with a view to identifying and sharing good practices, deriving actionable policy recommendations, strengthening institutional capacities, and experimenting new approaches. This will also help public authorities and agencies to design evidence-based and targeted policy interventions in the long-term, including updates to regional Smart Specialisation Strategies and related innovation policy frameworks.
Projects can offer an added value when promoting the participation of EU outermost regions and addressing their specific needs. Due consideration will be given to such added value during the evaluation of I3 project proposals. Projects can also offer an added value when supporting regions with specific challenges, such as difficulties in retaining and attracting talents. I3 Instrument, in particular Strand 2b, is integral part of support on the ground offered by the European Commission to cities, regions and Member States, through the Talent Booster Mechanism where I3 Instrument with its capacity building component represents one of the pillars.
Proposals submitted under this call for proposals shall:
Help create connected and well-performing regional innovation ecosystems, establishing the right framework conditions for interregional cooperation. This improved connectivity should support regions in aligning their innovation capacities and governance models to enable joint interregional innovation activities.
Contribute to the preparation of interregional innovation projects in shared smart specialisation areas. Proposals should lay the groundwork for future cooperation, in particular under Strand 2a, by focusing on areas of common interest and complementary strengths.
Facilitate the validation process of investment ideas through improved knowledge and practical skills in business and investment planning. This should include building concrete capacities by working with companies, in particular SMEs, in a specific value chain and defining a clear path towards developing I3 application(s).
Identify and address gaps and business opportunities that may hinder or enable the reinforcement of existing value chains or the creation of new ones. A clear link to smart specialisation priorities and value chain positioning is expected.
Experiment with “out-of-the-box” approaches to deliver validated solutions and tested models that can increase the capacity of regional actors to engage effectively in interregional innovation processes.
Ensure that the knowledge and capabilities gained during the project can be replicated, adapted, and embedded in the regional ecosystem. This should contribute to long-term institutional learning, inform updates to Smart Specialisation Strategies, and support policy and ecosystem development beyond the project’s lifetime.
Ensure the active involvement of companies and civil society, alongside public administrations, academia, and other quadruple-helix stakeholders.
To support the EU’s efforts to strengthen competitiveness and resilience, this call for proposals focuses on practical ways to improve how regions work together on innovation. This call focuses on creating the right conditions for technological progress and stronger innovation ecosystems, which are essential for building interregional innovation investment capacity.
Aligned with the Competitiveness Compass priorities — closing the innovation gap, decarbonising the economy, and reducing strategic dependencies — the call aims to support projects that remove innovation barriers — such as fragmented ecosystems, limited investment readiness, and weak links to European value chains.
Successful projects improve the innovation and coordination capacity of all participating reinforce the competitiveness and resilience of regional innovation ecosystems, boost regional competitiveness and support SMEs. Priority is given to capacity building and investment-readiness efforts in shared smart specialisation areas, with a view to enabling interregional cooperation and better integration into EU value chains.
Thematic areas of focus (non-exhaustive list):
Strengthening regional innovation ecosystems by engaging stakeholders, improving governance, and reinforcing interregional links, particularly for less developed regions, to better connect with EU value chains. This can also involve using technical assistance from mainstream ERDF programmes to help public bodies structure and strengthen local ecosystems, improve framework conditions, and address governance or coordination challenges.
Increasing investment readiness through improved business and investment planning, building concrete capacities in SMEs and other actors, and enabling participation in interregional partnerships.
Facilitating knowledge and talent mobilisation, recognising human capital as a key driver of competitiveness and innovation, and promoting measures to retain, attract, and develop skills.
Enhancing value chain integration through ecosystem building and S3 partnerships to overcome fragmentation and reduce the innovation divide.
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Expected effects and impacts
Long term impact (non-exhaustive list)
- Committed innovation intermediaries (e.g. regional development agencies, industrial associations) to support companies engaging in innovation and interregional value chains.
- Increased capacity of regional ecosystems to contribute to Europe’s innovation competitiveness through participation in interregional investment projects.
- Improved support measures for innovation diffusion, investment identification, interregional collaboration, and value chain participation.
- Improved cooperation with interregional ecosystems to de-risk investments and leverage European innovation and market potential
- Improved business climate for competitive ecosystems, including support to industries with corporate strategies in key thematic areas (such as innovation investments, internationalisation, customer orientation in EU and global markets, and personnel training through upskilling and reskilling).
- Reinforced cooperation capacity of quadruple-helix ecosystems in participating regions.
- Reinforced capacity to engage with local SMEs and collaborate with other ecosystems (e.g. to address interregional investments on shared S3 priorities) and improved connections among innovation stakeholders within interregional quadruple-helix ecosystems.
- Increased readiness of I3 consortia to cooperate in globally competitive EU value chains.
Proposals shall identify relevant KPIs and indicate targets that consortia plan to reach. All KPIs relate to the situation at the end of each project.
Output KPIs must be measured at the beginning and at the end of the project. The following 4 KPIs dimensions have been identified:
- Interregional dimension
- Number of regions at different level of development.
- Policy dimension
- Number of S3 Partnerships (or other relevant interregional working groups in networks and platforms) in which regions are actively participating;
- Number of policy measures conceived to engage the ecosystems externally.
- Socio-economic dimension
- Number of value chain analyses based on mapping and benchmarking activities;
- Number of business cases identified in the framework of the given value chain developed;
- Number of companies involved in the business cases;
- Number of intermediaries engaged in interregional activities;
- Number of interregional alliances established or in preparation.
- Gender dimension in innovation ecosystems (increasing women participation and gender mainstreaming), e.g:
- Fixed targets in women’s participation (e.g. women innovators involved);
- Number of gender equality measures in participating organisations;
- Gender-specific innovations (valorising knowledge based on gender and intersectional analysis).
Consortia are invited and encouraged to identify and measure tailored KPIs (quantitative and qualitative) in addition to the listed ones.
These can include action plans, indicators related to specific business cases, indicators on quadruple helix stakeholders’ engagement, and ecosystem governance arrangements.
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Expected results
Eligible activities include coordination and support actions targeting regional actors — such as small and medium-sized enterprises, research infrastructures, clusters, innovation agencies, ERDF managing authorities, and other organisations active in business development, territorial cooperation, or innovation. These activities aim at strengthening regional innovation ecosystems and improving the ability to identify relevant investment portfolios for future applications under the I3 Instrument (Strands 1 and 2a) or other EU funding schemes.
To promote a balanced approach and ensure a broader impact, proposals must include at least one core action and may be complemented by support actions. There is no obligation to cover all actions listed below, as these are indicative groupings to help structure the scope of activities.
A-Core actions
1-Ecosystem Building and Connection
- Activating innovation intermediaries - Mobilising regional development agencies, clusters, and private sector organisations to engage local stakeholders in interregional cooperation and investment processes.
- Creating and reinforcing resilient interregional innovation ecosystems - Actions that help regions strengthen their innovation ecosystems internally by building collaboration among key stakeholders and addressing fragmentation.
- Cooperating with industry associations, Technology Transfer Offices and other key players at local/regional level - Facilitate collaboration with business networks, clusters, research institutions and Innovation intermediaries to improve quadruple-helix connections.
- Developing tools and know-how for participation in alliances and networks - Design instruments that enable ecosystem actors to join European and global networks, enhancing cooperation in shared S3 domains.
- Designing the policy mix for innovation and internationalisation in SMEs - Develop frameworks that support SMEs in accessing EU and global value chains, including policies for innovation uptake.
- Designing knowledge transfer activities - Foster mutual learning within and beyond the consortium through structured knowledge exchange with regional and national actors.
- Testing and piloting ecosystem initiatives - Pilot new support schemes or cooperation mechanisms to improve innovation ecosystem coordination and prepare for future interregional projects.
- Designing and piloting talent attraction and retention initiatives - Develop and test measures to strengthen the regional workforce and align skills with smart specialisation priorities.
2-Investment Project Identification
- Designing industry-driven value chain initiatives - Identify and shape interregional value chains aligned with S3 priorities, building on regional strengths and complementarity.
- Innovative project feasibility assessment - Support early-stage work to assess market, technological, and business feasibility of potential investment projects.
- Funding mix identification - Prepare optimal financing structures, evaluate investment-readiness, and map possible co-financing sources across programmes.
- Legal and technical support - Address regulatory, legal or technical aspects of proposed project ideas.
B-Support actions
1-Mapping, Benchmarking and Matchmaking
- Mapping and benchmarking regional innovation performance - Use tools such as the Regional Innovation Scoreboard (RIS), European Innovation Scoreboard (EIS) and Community Innovation Survey (CIS), to assess and compare the performance of local innovation actors.
- Analysing interregional value chains and sub-value chain niches - Identify challenges, gaps, and opportunities for regional ecosystems to engage in emerging or strategic value chains.
- Matching supply-side competencies with business opportunities - Map regional strengths and connect them with demand-driven investment opportunities across regions.
- Mapping skills gaps and talent pipelines - Identify regional skills gaps and labour market needs relevant to targeted value chains, and map potential talent pipelines to support ecosystem development.
2-Networking and Staff Exchange
- Strengthening participation in EU networks and platforms - Support integration into S3 Thematic Platforms, European Technology Platforms, the EU Cluster Collaboration Platform and other relevant networks.
- Fostering staff exchange and talent development
- Identify skills gaps and talent needs and implement staff exchange and peer learning to strengthen human capital and transfer know-how across ecosystems.
- Enabling cluster and company missions across regions - Organise business or cluster visits to other regions or Member States, including visits to demonstration infrastructure.
- Connecting regional ecosystems through twinning activities - Facilitate direct cooperation between innovation ecosystems, including business and research actors.
- Building capacity of innovation managers and business developers - Equip key innovation actors with the skills and tools to engage in interregional investment processes.
Project proposals must describe in detail the coordinator's role and have to ensure shared understanding among all project members about the project tasks and responsibilities. For this purpose, when needed, consortium coordinators can delegate specific tasks and responsibilities to project partners, leveraging their expertise and resources to ensure successful implementation.
Consortia are encouraged to elaborate an exploitation plan which lays out how the project will tap into opportunities for further funding under the European Regional Development Fund (ERDF) and how it will explore synergies with the ERDF and other EU funding programmes and instruments (in particular with the Interreg Europe programmes). In addition, the consortia shall explain how they assure sustainability and a lasting effect on the regional innovation ecosystems.
Project proposals shall detail how the project will ensure the collaboration with the Enterprise Europe Network (e.g. the EEN Sector and thematic groups), European Innovation Ecosystem stakeholders, Horizon Europe partnerships, S3 Community of Practice (S3 COP) and other relevant networks or partnerships. All proposed actions shall capitalise on already available information and should not be limited to duplicating what already exists.
Consortia are encouraged to develop dissemination strategies, going beyond traditional channels e.g. using social media platforms and events to promote EU funded activities for public awareness and engage a broader community through cross learning.
In line with the specific objectives of this call for proposals, the expected outputs have to refer to the following output:
- Concrete output at the closure of the project (non-exhaustive list):
- Tailored policy measures (in place or ready for adoption) to increase the innovation capacity of ecosystems and their ability to participate in interregional innovation projects.
- Cooperation arrangements with industry associations and other key players to enable participation in international expert networks and regional alliances.
- Agreements with suitable partners for cooperation with less developed regions on specific innovation topics.
- Membership in relevant networks and innovation thematic platforms supporting 1) innovation diffusion or 2) the development of policy measures to foster investments, open new markets, and promote value chain participation.
- Tested tools for mapping demand-driven business opportunities for interregional investments and matching them supply-side competencies.
- Identified pipeline for I3 investment projects based on value chain mapping and benchmarking activities.
- Identified innovative and competitive products and services relevant for interregional and European value chains.
- Concrete business cases prepared to apply to I3 investment calls.
- Increased innovation maturity of business cases (technology readiness, business readiness, and market readiness).
- Dissemination plan for sharing best practice examples, showcasing results, and promoting uptake and replication of I3 project outcomes.
- Exploitation plan for scaling up project results and leveraging further ERDF mainstream programme funding.
In addition, you will be expected to submit one progress report not linked to payments and a report on annual cumulative expenditure.
The outcome of Strand 2b projects is expected to be the increased capacities of less developed regions. Regional innovation ecosystems are expected to strengthen their capacity to deliver concrete interregional innovation investments within EU value chains and the capacity to tap into other funding instruments, to cover additional funding needs (if necessary). Upon project completion, involved SMEs will possess enhanced capacity to cooperate in interregional value chains and to attract private investments or to create public- private partnerships.
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Eligibility Criteria
Regions / countries for funding
eligible entities
Education and training institution, International organization, Non-Profit Organisation (NPO) / Non-Governmental Organisation (NGO), Other, Private institution, incl. private company (private for profit), Public Body (national, regional and local; incl. EGTCs), Research Institution incl. University, Small and medium-sized enterprise (SME)
Mandatory partnership
Yes
Project Partnership
In order to be eligible, the applicants (beneficiaries and affiliated entities) must:
- be legal entities (public or private bodies)
- be established in one of the eligible countries, i.e.:
- EU Member States (including overseas countries and territories (OCTs))
- listed EEA countries and countries associated to the I3 Instrument or countries which are in ongoing negotiations for an association agreement and where the agreement enters into force before grant signature (list of participating countries)
Specific cases
Entities from other countries (not listed above) are exceptionally eligible, if the granting authority considers their participation essential for the implementation of the action.
Natural persons are NOT eligible (with the exception of self-employed persons, i.e. sole traders, where the company does not have legal personality separate from that of the natural person).
International organisations are eligible. The rules on eligible countries do not apply to them.
Entities which do not have legal personality under their national law may exceptionally participate, provided that their representatives have the capacity to undertake legal obligations on their behalf, and offer guarantees for the protection of the EU financial interests equivalent to that offered by legal persons.
EU bodies (with the exception of the European Commission Joint Research Centre) can NOT be part of the consortium.
Entities composed of members may participate as ‘sole beneficiaries’ or ‘beneficiaries without legal personality’. Please note that if the action will be implemented by the members, they should also participate (either as beneficiaries or as affiliated entities, otherwise their costs will NOT be eligible).
EU restrictive measures — Special rules apply for entities subject to EU restrictive measures under Article 29 of the Treaty on the European Union (TEU) and Article 215 of the Treaty on the Functioning of the EU (TFEU). Such entities are not eligible to participate in any capacity, including as beneficiaries, affiliated entities, associated partners, subcontractors or recipients of financial support to third parties (if any).
EU conditionality measures — Special rules apply for entities subject to measures adopted on the basis of EU Regulation 2020/209211. Such entities are not eligible to participate in any funded role (beneficiaries, affiliated entities, subcontractors, recipients of financial support to third parties, etc). Currently such measures are in place for Hungarian public interest trusts established under the Hungarian Act IX of 2021 or any entity they maintain (see Council Implementing Decision (EU) 2022/2506, as of 16 December 2022).
other eligibility criteria
Proposals must be submitted by a consortium of applicants (beneficiaries; not affiliated entities), which complies with all the following conditions:
- minimum two independent legal entities representing two regional ecosystems from two different eligible countries,
- representing at least one “less developed region” and one “more developed region” of an EU Member State,
- include quadruple-helix innovation actors such as public administrations, research and academia, industry, and end users,
- include innovation intermediaries with an umbrella role (e.g. clusters representing companies, universities, RTOs) to maximise the representation of quadruple helix stakeholders from less developed regions,
- the coordinator must be established in an EU Member State from a “less developed region” or “outermost region” and either be
- a public body, or a
- non-for-profit organisation, or an
- entity entrusted by a national or regional government to develop or implement innovation and investment actions for SMEs (i.e. cluster organisations, public private partnerships, development agencies, innovation agencies etc.), or a
- Member State Organisation acting under indirect management, or
- European association or international organisation.
Additional information
Topics
Relevance for EU Macro-Region
EUSAIR - EU Strategy for the Adriatic and Ionian Region, EUSALP - EU Strategy for the Alpine Space, EUSBSR - EU Strategy for the Baltic Sea Region, EUSDR - EU Strategy for the Danube Region
UN Sustainable Development Goals (UN-SDGs)
project duration
between 18 and 24 months
Additional Information
Proposals must be submitted electronically via the Funding & Tenders Portal Electronic Submission System (accessible via the Topic page in the Calls for proposals section).
Proposals must be complete and contain all the requested information and all required annexes and supporting documents:
- Application Form Part A — contains administrative information about the participants (future coordinator, beneficiaries and affiliated entities) and the summarised budget for the project (to be filled in directly online)
- Application Form Part B — contains the technical description of the project (template to be downloaded from the Portal Submission System, completed, assembled and re-uploaded)
- Mandatory annexes and supporting documents (templates to be downloaded from the Portal Submission System, completed, assembled and re-uploaded):
- detailed budget table (template available in the Submission System)
- Endorsement letter (mandatory letter from the Member States’ or regional competent body responsible for the smart specialisation strategy (S3); template available in the Submission System). The endorsement letter is required at appropriate NUTS level14 (NUTS level I, II or III) depending on the context of each Member State and/or region. This is required for all consortium members to confirm the alignment with the national or regional S3 policies15, strategies and priorities of all Member States and Regions represented by organisations participating in this application.
Proposals are limited to maximum 70 pages (Part B).
Financial support to third parties is NOT allowed.
Call documents
Call Document I3-2026-CAP2bCall Document I3-2026-CAP2b(344kB)
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