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  1. An institution, body, office or agency established by or based on the Treaty on European Union and the Treaties establishing the European Communities.

    All education and training facilities for people of different age groups.

    An intergovernmental organization having legal personality under public international law or a specialized agency established by such an international organization. An international organization, the majority of whose members are Member States or Associated Countries and whose main objective is to promote scientific and technological cooperation in Europe, is an International Organization of European Interest.

    An NPO is an institution or organization which, by virtue of its legal form, is not profit-oriented or which is required by law not to distribute profits to its shareholders or individual members. An NGO is a non-governmental, non-profit organization that does not represent business interests. Pursues a common purpose for the benefit of society.

    A partnership, corporation, person, or agency that is for-profit and not operated by the government.

    Any government or other public administration, including public advisory bodies, at the national, regional or local level.

    A research institution is a legal entity established as a non-profit organization whose main objective is to conduct research or technological development. A college/university is a legal entity recognized by its national education system as a university or college or secondary school. It may be a public or private institution.

    A microenterprise, a small or medium-sized enterprise (business) as defined in EU Recommendation 2003/361. To qualify as an SME for EU funding, an enterprise must meet certain conditions, including (a) fewer than 250 employees and (b) an annual turnover not exceeding EUR 50 million and/or an annual balance sheet total not exceeding EUR 43 million. These ceilings apply only to the figures for individual companies.

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  1. Administration & Governance, Institutional Capacity & Cooperation 

    This topic focuses on strengthening governance, fostering institutional capacity, and enhancing cross-border cooperation. It includes promoting multilevel, transnational, and cross-border governance by designing and testing effective structures and mechanisms, as well as encouraging collaboration between public institutions on various themes. 

    Innovation capacity and awareness are also key, with actions aimed at increasing the ability of individuals and organizations to adopt and apply innovative practices. This involves empowering innovation networks and stimulating innovation across different sectors. 

    Institutional cooperation and network-building play a crucial role, supporting long-term partnerships to improve administrative processes, share regional knowledge, and promote intercultural understanding. This also includes cooperation between universities, healthcare facilities, schools, sports organizations, and efforts in management and capacity building. 

    This topic focuses on strengthening the agricultural, forestry, and fisheries sectors while ensuring sustainable development and environmental protection. It covers agricultural products (e.g., fruits, meat, olives), organic farming, horticulture, and innovative approaches to sustainable agriculture. It also addresses forest management, wood products, and the promotion of biodiversity and climate resilience in forestry practices.

    In the food sector, the focus lies on developing sustainable and resilient food chains, promoting organic food production, enhancing seafood products, and ensuring food security and safety. Projects also target the development of the agro-food industry, including innovative methods for production, processing, and distribution.

    Fisheries and animal management are essential aspects, with an emphasis on sustainable fishery practices, aquaculture, and animal health and welfare. This also includes efforts to promote responsible fishing, marine conservation, and the development of efficient resource management systems.

    Soil and air quality initiatives play a crucial role in environmental protection and public health. This includes projects aimed at combating soil and air pollution, implementing pollution management systems, and preventing soil erosion. Additionally, innovative approaches to improving air quality—both outdoors and indoors—are supported, alongside advancing knowledge and best practices in soil and air management.

    This topic focuses on protecting the environment, promoting biodiversity, and addressing the challenges of climate change and resource management. It includes efforts to mitigate and adapt to climate change, develop low-carbon technologies, and reduce GHG emissions. Biodiversity promotion and natural protection are key aspects. 

    It also covers improving soil and air quality by reducing pollution, managing contamination, preventing soil erosion, and enhancing air quality both outdoors and indoors. Water management plays an essential role, including sustainable water distribution, monitoring systems, innovative wastewater treatment technologies, and water reuse policies. Additionally, it addresses the protection and development of waterways, lakes, and rivers, as well as sustainable wetland management. 

    This topic focuses on preserving, promoting, and enhancing cultural and natural heritage in a sustainable way. It includes efforts to increase the attractiveness of cultural and natural sites through preservation, valorisation, and the development of heritage objects, services, and products. Cultural heritage management, arts, and culture play a key role, including maritime heritage routes, access to cultural sites, and cultural services like festivals, concerts, and art workshops. 

    Tourism development is also central, with actions aimed at promoting natural assets, protecting and developing natural heritage, and increasing touristic appeal through the better use of cultural, natural, and historical heritage. It also covers the improvement of tourist services and products, the creation of ecotourism models, and the development of sustainable tourism strategies. 

    This topic focuses on the sustainable management, protection, and valorisation of natural resources and areas, such as habitats, geo parks, and protected zones. It also includes preserving and enhancing cultural and natural heritage, landscapes, and protecting marine environments. 

    Circular economy initiatives play a key role, with actions aimed at innovative waste management, ecological treatment techniques, and advanced recycling systems. Projects may focus on improving recycling technologies, organic waste recovery, and establishing repair and re-use networks. Additionally, pollution prevention and control efforts address ecological economy practices, marine litter reduction, and sustainable resource use. 

    This topic covers labour market development and employment, focusing on creating job opportunities, optimizing existing jobs, and addressing academic (un)employment and job mobility. It also includes attracting a skilled workforce and improving working conditions for various groups. 

    Strengthening small and medium-sized enterprises (SMEs) and boosting entrepreneurship are key priorities. This includes enhancing SME capacities, supporting social entrepreneurship, and promoting innovative business models. Activities may focus on creating advisory systems for start-ups, spin-offs, and incubators, fostering business networks, and improving the competitiveness of SMEs through knowledge and technology transfer, digital transformation, and sustainable business practices. 

    This topic focuses on fostering community integration and strengthening a common identity by promoting social cohesion, positive relations, and the development of shared spaces and services. It supports initiatives that enhance intercultural understanding and cooperation between different societal groups. 

    Demographic change and migration address key societal challenges, such as an aging population, active aging, and silver economy strategies. It also includes adapting public services and infrastructure to demographic shifts, tackling social and spatial segregation, and addressing brain drain. Migration-related actions cover policy development, strategic planning, and the integration of migrants to create inclusive and resilient communities. 

    All projects where ICT has a significant role, including tailor-made ICT solutions in different fields, as well as digital innovation hubs, open data, Internet of Things; ICT access and connecting (remote) areas with digital infrastructure and services; services and applications for citizens (e-health, e-government, e-learning, e-inclusion, etc.); services and applications for companies (e-commerce, networking, digital transformation, etc.).

    This is about the mitigation and management of risks and disasters, and the anticipation and response capacity towards the actors regarding specific risks and management of natural disasters, for example, prevention of flood and drought hazards, forest fire, strong weather conditions, etc.. It is also about risk assessment and safety.

    This topic focuses on enhancing education, training, and opportunities for children, youth, and adults. It covers the expansion of educational access, reduction of barriers to education, and improvement of higher education and lifelong learning. It also includes vocational education, common learning programs, and initiatives supporting labour mobility and educational networks. Additionally, it addresses the promotion of media literacy, digital learning tools, and the development of innovative educational approaches to strengthen knowledge, skills, and societal participation. 

    This topic emphasizes the role of culture and media in education and social development. It supports initiatives that foster creativity, cultural awareness, and artistic expression among children and youth. Activities include promoting cross-border cooperation in the audiovisual sector, enhancing digital content creation skills, and boosting the distribution of educational and cultural media products. Furthermore, it encourages the development of media literacy initiatives, helping young audiences critically engage with digital and media content. By connecting education, creativity, and media, this topic strengthens cultural identity and supports inclusive, knowledge-based societies. 

    This topic covers actions aimed at improving energy efficiency and promoting the use of renewable energy sources. It includes energy management, energy-saving methods, and evaluating energy efficiency measures. Projects may focus on the energy rehabilitation and efficiency of buildings and public infrastructure, as well as promoting energy efficiency through cooperation among experienced firms, institutions, and local administrations. 

    In the field of renewable energy, this encompasses the development and expansion of wind, solar, biomass, hydroelectric, geothermal, and other sustainable energy sources. Activities include increasing renewable energy production, enhancing research capacities, and developing innovative technologies for energy storage and management. Projects may also address sustainable regional bioenergy policies, financial instruments for renewable energy investments, and the establishment of cooperative frameworks for advancing renewable energy initiatives. 

    This topic focuses on promoting equal rights and strengthening social inclusion, particularly for marginalized and vulnerable groups. It covers activities enhancing the capacity and participation of children, young people, women, elderly people, and socially excluded groups. Activities can address the creation of inclusive infrastructure, improving access and opportunities for people with disabilities, and fostering social cohesion through innovative care services. It also includes initiatives supporting victims of gender-based violence, promoting human rights, and developing policies and tools for social integration and equal participation in society. 

    This area focuses on improving health and social services, enhancing accessibility and efficiency for diverse groups such as the elderly, children, and people with disabilities. It includes the development of new healthcare models, innovative medical diagnostics and treatments (e.g., dementia, cancer, diabetes), and the management of hospitals and care facilities. Additionally, activities addressing rare diseases, promoting overall wellbeing, and fostering preventive health measures fall under this theme. It also covers sports promotion, encouraging physical activity as a means to improve public health and social inclusion. 

    This area focuses on strengthening justice, safety, and security through cross-border cooperation and institutional capacity-building. It includes initiatives aimed at improving the efficiency and effectiveness of police, fire, and rescue services, enhancing civil protection systems, and rapid response capabilities for emergencies like chemical, biological, radiological, and nuclear incidents. Activities also target the prevention and combatting of organized crime, drug-related crimes, and human trafficking, as well as ensuring secure and efficient border management. Furthermore, it covers initiatives promoting the protection of citizens, community safety, and the development of innovative security services and technologies. 

    This area focuses on the development and improvement of transport and mobility systems, covering all modes of transport, including urban mobility and public transportation. Actions aiming at improving transport connections through traffic and transport planning, rehabilitation and modernisation of infrastructure, better connectivity, and enhanced accessibility. Projects promoting multimodal transport and logistics, optimising intermodal transport chains, offering sustainable and efficient logistics solutions, and developing multimodal mobility strategies. Also, initiatives establishing cooperation among logistic centres and providing access to clean, efficient, and multimodal transport corridors and hubs. 

    Activities focusing on the sustainable development and strategic planning of urban, regional, and rural areas. This includes urban development such as city planning, urban renewal, and strengthening urban-rural links through climate adaptation, sustainable mobility, water efficiency, participatory processes, smart cities, and the regeneration of public urban spaces. Regional planning and development cover the implementation of regional policies and programmes, sustainable land use management plans, integrated regional action plans, spatial planning, and the efficient management of marine protected areas. Rural and peripheral development addresses the challenges of remote and sparsely populated areas by fostering rural community development, enhancing rural economies, improving access to remote regions, and promoting tailored policies for rural sustainability and growth. 

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Call key data

Transformative Healthcare Instrument 2026

Funding Program

European Institute of Innovation and Technology

deadlines

Opening
24.06.2026

Deadline
16.09.2026 16:00

Funding rate

50%

Call budget

€ 5,000,000.00

Estimated EU contribution per project

between € 300,000.00 and € 500,000.00

Link to the call

Link to the submission

Call content

short description

EIT Health is offering between €300,000 and €500,000 in funding to support high-potential European start-ups developing innovative solutions in biotech, medtech, digital health, AI, and biomarkers or diagnostics. The programme is designed to help companies advance product development, strengthen commercialisation strategies, and prepare for their next stage of fundraising while addressing unmet clinical needs across Europe.

Expected effects and impacts

This call aims to strengthen integration between the research and business sides of the knowledge triangle by accelerating healthcare innovations borne out of research to support commercial and business growth of small and micro enterprises in European markets. All funded projects under this Call are expected to generate the following outcomes and long-term impact.

  • Commercial acceleration, including attracting additional funding, closing future venture capital investments, and growing revenue (where applicable).
  • Developing and accelerating new health innovations with high potential to positively impact the lives of the citizens of Europe, as well as to generate financial returns.
  • Protection of new innovations and micro, small, and medium enterprises (SME´s) via intellectual property (IP) strategy.

Proposals must clearly and credibly articulate the path to achieving such impact, which may be reported up to three years after the end of the EIT Health funding period. Please refer to sections 2.3.3 on Key Performance Indicators (KPIs) and 7.2 on Monitoring for more information on the contractual obligations of projects to report achieved impacts during and after the project funding period.

Extension or continuation of projects will be tied to the conditions described in section 3.10 Fast Track Mechanism and Additional Project Funding.

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Expected results

The Transformative Health Instrument (THI) call invites micro, small, and medium enterprises (SMEs) to submit applications for funding to support the development of scalable health technologies in Biotech, Medtech, Digital Health & AI, Biomarker / Diagnostics or a combination of these. Applicants should address unmet needs in Europe with novel and commercially viable approaches, scientific excellence, and strong internal capabilities.

Depending on the focus of the company, applicants’ solutions must be at the following innovation maturity levels (IML) at the time of application: 

  • IML ≥ 5 for Biotech (Safety/Toxicity study stage).
  • IML≥ 6 in Medtech (Initial clinical PoC).
  • IML ≥ 7 for Digital (Market validation).
  • IML ≥ 7 for Biomarker Diagnostics.

The following types of innovations are out of scope:

  • A non-medical device or application.
  • A product primarily designed for wellness or lifestyle purposes that can be used without medical oversight.
  • Companies that do not target the European market.

The funded innovation must be premised on a viable existing or future business model and a legally registered, for-profit entity with the proper capabilities to develop, market and scale the solution.

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Eligibility Criteria

Regions / countries for funding

EU Member States, Overseas Countries and Territories (OCT)
Moldova (Moldova), Albania (Shqipëria), Armenia (Հայաստան), Azerbaijan (Azərbaycan), Bosnia and Herzegovina (Bosna i Hercegovina / Босна и Херцеговина), Canada, Faeroes (Føroyar / Færøerne), Georgia (საქართველო), Iceland (Ísland), Israel (ישראל / إِسْرَائِيل), Kosovo (Kosova/Kosovë / Косово), Montenegro (Црна Гора), Morocco (المغرب), New Zealand (Aotearoa), North Macedonia (Северна Македонија), Norway (Norge), Serbia (Srbija/Сpбија), Tunisia (تونس /Tūnis), Türkiye, Ukraine (Україна), United Kingdom

eligible entities

Small and medium-sized enterprise (SME)

Mandatory partnership

No

Project Partnership

For this call, a ‘legal entity’ means a legal entity created and recognised as such under national law, EU law or international law, which has legal personality and which may, acting in its own name, exercise rights and be subject to obligations, or an entity without legal personality.

In accordance with the Horizon Europe Work Programme 2025 6, to be eligible for funding, the applicant must be established in one of the eligible countries, specifically:

  • the Member States of the European Union, including their outermost regions;
  • the Overseas Countries and Territories (OCTs) linked to the Member States;
  • countries associated to Horizon Europe;
  • certain low- and middle-income countries.

Individuals cannot apply for funding under this call.

Companies must meet the below conditions to be eligible for funding. Only companies satisfying all the below criteria will move to the evaluation stage. The following requirements and definitions shall apply to all applicants:

  • The entity is a legally registered for-profit micro, small, or medium enterprise according to the European Commission SME definition.
    • The entity must have at least 4 full-time equivalent (FTE), permanent employees who are compensated on a salaried basis, and are contracted to spend at least 50% of their total working time for the entity at the time of proposal submission. Staff hired as consultants or freelancers are not counted as permanent or salaried staff. The employment status of staff must be demonstrable through payroll records and employment contracts with the company upon request. This condition does not apply to the company Chief Executive Officer (CEO).
    • The entity must have a CEO engaged on a full-time basis at the time of proposal submission. The CEO may be employed under an employment contract or engaged through an equivalent full-time arrangement (e.g. director mandate, management services agreement, founder-director role, or secondment), provided that the CEO is fully dedicated to the entity’s operations. Evidence of such engagement (e.g. employment contract, service agreement, appointment documentation or equivalent) must be available upon request.
    • The entity cannot have publicly traded shares or be in the process of an Initial Public Offering (IPO).
    • The assessment of the entity should be done at the parent (holding) company level, if the governance structure of the SME involves a holding structure.
  • The company must have successfully closed an equity funding round (Qualified Investment Round) in the last 36 months by the application deadline, where the round meets the following conditions:
    • A minimum total investment of 2,000,000 EUR within a 36-month period, with at least one new investor contributing.
    • At least one of the new investors in the Qualified Investment Round must be a qualified, privately managed, profit-oriented, professional investor investing from a fund backed by Limited Partner (LP) commitments, including but not limited to independent European venture capital firms, firms managing alternative investment funds, and those investing private capital in early‑ and growth‑stage technology companies.
    • The Qualified Investment Round must be a priced round with a set valuation. Funding rounds via a convertible note or Simple Agreement for Future Equity (SAFE) do not qualify.

other eligibility criteria

The THI is intended to support private companies, specifically Micro, Small and Medium-sized enterprises (SMEs), with at least 4 full-time equivalent employees. Eligible companies must have closed a minimum total equity investment of 2,000,000 EUR within the previous 36-months, with at least one new investor contributing. Funded projects must be at the Innovation Maturity Levels (IML) listed below, depending on their industry focus:

  • IML ≥ 5 for Biotech (Safety/Toxicity study stage).
  • IML≥ 6 in Medtech (Initial clinical PoC)
  • IML ≥ 7 for Digital (Market validation)
  • IML ≥ 7 for Biomarker / Diagnostics

Additional information

Topics

Competitiveness of Enterprises, Employment/Labour Market, SME & entrepreneurship, 
Health, Social Services, Sports

Relevance for EU Macro-Region

EUSAIR - EU Strategy for the Adriatic and Ionian Region, EUSALP - EU Strategy for the Alpine Space, EUSBSR - EU Strategy for the Baltic Sea Region, EUSDR - EU Strategy for the Danube Region

UN Sustainable Development Goals (UN-SDGs)

project duration

12 months

Additional Information

  • Step 1: Register your organisation in the EU Funding & tender opportunities portal to obtain the nine-digit Participant Identification Code (PIC number). If you do not know if your organisation already has a PIC number, you can verify directly on the EU Portal whether your organisation is already registered.
  • Step 2: Apply to the call via EIT Health’s application platform. Click on the “Apply” button below.

Contact

European Institute of Innovation & Technology
+36 14 819 300
Website